[iv] Hussein M Dashti, MD PhD FICS FACS, Thazhumpal C Mathew, MSc PhD FRCPath, Talib Hussein, MB ChB, Sami K Asfar, MB ChB MD FRCSEd FACS, Abdulla Behbahani, MB ChB FRCS FACSI PhD FICS FACS, Mousa A Khoursheed, MB ChB FRCS FICS, Hilal M Al-Sayer, MD PhD FICS FACS, Yousef Y Bo-Abbas, MD FRCPC, and Naji S Al-Zaid, BSc PhD. "Long-term effects of a ketogenic diet in obese patients"


A ketogenic diet helps control blood sugar levels. It is excellent for managing type 2 diabetes, sometimes even leading to complete reversal of the disease. This has been proven in studies. It makes perfect sense since keto lowers blood-sugar levels, reduces the need of medications and reduces the potentially negative impact of high insulin levels.
Oh my god! This is one of those ˜Too-good-to-be-free' comprehensive resources. I've been following your content and I wonder why you give away so much well researched info for free. Anyway, that's a pretty damn good job you've done here. Until I read this, I was floundering with so much bit sized confusing information out there. You've literally dumbed it down for me. I'm off to take my measurements before I start the diet! Thanks a ton!!!
A œmoderate keto diet is an option that can still encourage substantial weight loss and other improvements in symptoms. A moderate keto diet includes more foods with carbs and, therefore, more fiber too. Carbs are usually increased to about 30“50 net grams per day, which means foods like more high-fiber veggies, some fruit or some starchy veggies can also be included.

Clinical improvement was observed in Alzheimer's patients fed a ketogenic diet, and this was marked by improved mitochondrial function. (14a) In fact, a European Journal of Clinical Nutrition study pointed to emerging data that suggested the therapeutic use of ketogenic diets for multiple neurological disorders beyond epilepsy and Alzheimer's, including headaches, neurotrauma, Parkinson's disease, sleep disorders, brain cancer, autism and multiple sclerosis. (14b)
For people with diabetes, rapidly rising ketone levels can signal a health crisis that requires immediate medical attention. When there is an absence or not enough of the hormone insulin (or the body is too resistant to insulin to allow it to drive glucose into the cells for energy), the body cannot use glucose for fuel. Insulin helps ferry glucose to our cells and muscles for energy. Instead, in this case, the body resorts to burning stored fat for energy through the process of ketosis, leading to a buildup of ketones in the body.
Here are a few of the most common side effects that I come across when people first start keto. Frequently the issues relate to dehydration or lack of micronutrients (vitamins) in the body. Make sure that you're drinking enough water (close to a gallon a day) and eating foods with good sources of micronutrients. To read more on micronutrients, click here >
Another great keto flu cure is bone broth! This is also a great healer when you are actually sick with a cold or flu or just want something comforting. Instead of its high carb alternative chicken noodle soup or even worse, store bought chicken broth (which is typically loaded with MSG and other preservative junk), bone broth is a delicious way to alleviate your flu symptoms. Bone broth is a great way to hydrate & it is also packed with electrolytes, good for you sodium and potassium.

If you're a newbie planning your weekly keto diet plan, make the meals as easy as possible. A keto breakfast, for example, can take advantage of many classic breakfast foods, including eggs, bacon, sausage, and ham. Eggs are real winners in the keto world. They're extremely versatile, easy to cook, and have just half a gram of carbs but 6 g of protein and 5 g of fat.

From the early understanding of the keto research and literature, it looks like we're just scratching the surface understanding some of the potential therapeutic roles of the keto diet. While it's unclear if it's any better or worse than any other diet for weight loss, the reality is that there is no one-size-fits-all model for diets. This doesn't even consider that weight-loss diets, in general, don't really work. While researchers can't agree on a specific statistic, it's commonly accepted that the vast majority of dieters will regain the weight lost (and often pack on extra pounds, as well). The long-term outcome of the keto diet is likely to be no different, especially given how challenging and restrictive it is to maintain.


The average person's diet contain about 55% carbohydrates, 30% fat, and 15% protein. On the keto diet, you eat a whole lot more fat, and a lot less carbs: 80% of the diet is comprised of fat, 15% is protein, and a mere 5% of calories come from carbohydrates. For someone on a 1,500-calorie diet, that translates to 19 grams of carbohydrates per day, which is less than what you find in one medium-sized apple.
Achieving ketosis is a pretty straightforward, but it can seem complicated and confusing with all of the information out there.4If you want to learn more about ketosis and the scientific process around it, you can visit a very in-depth discussion about on Dr. Peter Attia's website. Here's the bottom line on what you need to do, ordered in levels of importance:
On the other hand, the types of foods you'll avoid eating on the keto, low-carb diet are likely the same ones you are, or previously were, accustomed to getting lots of your daily calories from before starting this way of eating. This includes items like fruit, processed foods or drinks high in sugar, those made with any grains or white/wheat flour, conventional dairy products, desserts, and many other high-carb foods (especially those that are sources of œempty calories).
This is an adaptation period, where we're essentially re-training our muscles and our brain to use fat as the primary fuel source instead of glucose. This adaptation can take a couple of weeks to a couple of months. As a hallmark of being keto-adapted and not just in ketosis, the skeletal muscles are able to burn fat directly for fuel, and the brain relies on the higher volume of ketones in the blood as its main source of energy.
4) So, how are you feeling? Are you excited to see the numbers behind what you will be eating? You should be, because you are about to discover how you can lose weight, and still enjoy foods that taste amazing! This is going to be the last big project you complete before we get to the actual food, so head over to this post to set up My Fitness Pal Keto Diet Settings.
Cyclical ketogenic diet: The Bulletproof Diet falls into this category. You eat high fat, low carb (less than 50 grams of net carbs a day) five to six days of the week. On day seven, you up your carb intake to roughly 150 grams, during what's called a carb refeed day. Carb cycling this way helps you avoid the negative effects some people experience when they restrict carbs long term, like thyroid issues, fatigue and dry eyes.[10] [11] Full ketosis isn't for everyone, and adding carbs such as sweet potatoes, squash, and white rice one day a week keeps your body systems that need some amount of carbs functioning properly.
On this hack, participants are encouraged to eat eggs “ and a lot of them. The theme with these hacks and other short term solutions is limiting calories to 1000 or less, and this is no exception. While fried, scrambled, and poached are perfect options for this hack, there are many creative recipes where people have created desserts, beverages, and bread substitutes with eggs. This hack is also known as a stall breaker, so if you're stuck at a certain weight for three weeks or more, give the egg fast a try for a few days.
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œOne of the best meal planning tips I've ever received is to structure breakfast and lunch so that you don't have to think too much about it, says Emily Bartlett, co-founder of Real Plans. œIf you're okay with repetition, it's ideal to have a simple selection of recipes for breakfast”including some that can be taken on the go. For lunch, go ahead and use your leftovers with a fresh green salad, and be sure to include a dressing that you really love.
When carbs go missing from a person's diet, the body uses up its glucose reserves and then breaks down stored fat into fatty acids, which, when they reach the liver, are converted into an organic substance called ketones. The brain and other organs feed on ketones in a process called ketosis, which gives the diet its name. Keto dieters eat lots of fat to maintain this state.

It's important to remember that the goal of any dietary change is to promote a healthy lifestyle, so make sure to select a meal plan you can envision yourself following long term. If you know you will not be able to comply with such stringent carbohydrate restrictions for years to come, the ketogenic diet is most likely not the right choice for you.
Not necessarily. It ultimately depends on you. SOme people may thrive by regularly counting calories, while others see counting calories as something œboring. The key here, if you do not want to count calories, is to structure your plate in order to guarantee you are consuming enough fat. Just make sure that in every meal you are eating no more than a palm-full of protein, try to increase the amount of fat in your diet, and try to decrease the amount of carbohydrates.
The ketogenic diet for weight loss is based on the idea that driving the body into ketosis will maximize fat loss. Ketosis is a normal metabolic process that occurs when the body does not have enough glucose stores for energy. When these stores are depleted, the body resorts to burning stored fat for energy instead of carbs. This process produces acids called ketones, which build up in the body and can be used for energy. (2)

Con: Results can vary depending on how much fluid you drink. By drinking more water, you dilute the concentration of ketones in the urine and thus a lower level of ketones will be detected on the strips. The strips don't show a precise ketone level. Finally, and most importantly, as you become increasingly keto-adapted and your body reabsorbs ketones from the urine, urine strips may become unreliable, even if you're in ketosis.

¢ Cancer: Early experimental research suggests that the keto diet may have anti-tumor effects, likely because it reduces overall calorie intake (and circulating glucose) for tumor growth. In one 2014 review of animal research, a ketogenic diet was found to be successful at reducing tumor growth, colon cancer, gastric cancer and brain cancer. More research on humans with larger sample sizes is needed, but it's definitely food for thought.
There are variations of the ketogenic diet that are implemented for a variety of reasons. One of the top reasons these variations are used are for athletes who are not getting the necessary energy required for their intense workouts. There are also those who enjoy the benefits of ketosis, but they just do not feel the same without a carb refeed day every now and then.
Cyclical ketogenic diet: The Bulletproof Diet falls into this category. You eat high fat, low carb (less than 50 grams of net carbs a day) five to six days of the week. On day seven, you up your carb intake to roughly 150 grams, during what's called a carb refeed day. Carb cycling this way helps you avoid the negative effects some people experience when they restrict carbs long term, like thyroid issues, fatigue and dry eyes.[10] [11] Full ketosis isn't for everyone, and adding carbs such as sweet potatoes, squash, and white rice one day a week keeps your body systems that need some amount of carbs functioning properly.

There are numerous benefits that come with being on keto: from weight loss and increased energy levels to therapeutic medical applications. Most anyone can safely benefit from eating a low-carb, high-fat diet. Below, you'll find a short list of the benefits you can receive from a ketogenic diet. For a more comprehensive list, you can also read our in-depth article here >
It truly depends from person to person. While some may be able to stay in ketosis while consuming 80 grams of carbs, others may not be so lucky. Quite a lot of people within the population can go quite high in their carbohydrate consumption and stay in ketosis, granted they have no blood sugar dysregulation. The longer you have followed the keto diet, the more your metabolism remains in ketosis after a higher carb consumption.

Another third tip is snacking. Really important if you're a snacker and you are just starting your Ketogenic diet you'll probably need some form of snacks. Some of the best snacks for beginners include celery, nuts and nut-based hummus, cucumber. If you have more of a sweet-tooth, dark unsweetened chocolate is a great option, as is coconut or almond butter or even peanut butter.


First, let's start with the fact that most of the food in your cabinets just won't work anymore. They're not keto. Period. Lock them up, throw them out, donate them to a neighbor “ whatever you have to do to get them out of the house. In the first week, when you're craving carbohydrates, these foods will be the death of your ketogenic diet. Purge your pantry of carbohydrate foods!
This is of course just an overview of what you can eat, but these are things I'm most likely going to pick up from the grocery store. I also didn't want to include crazy expensive specialty items like Erythritol for beginners. I think we all get excited about making our favorite junk foods in the style of our diets right away. This is fine¦but it can be very expensive, time consuming and exhausting. Stik with the basics, especially when first starting out!

The keto diet (also known as ketogenic diet, low carb diet and LCHF diet) is a low carbohydrate, high fat diet. Maintaining this diet is a great tool for weight loss. More importantly though, according to an increasing number of studies, it helps reduce risk factors for diabetes, heart diseases, stroke, Alzheimer's, epilepsy, and more1-6.On the keto diet, your body enters a metabolic state called ketosis. While in ketosis your body is using ketone bodies for energy instead of glucose. Ketone bodies are derived from fat and are a much more stable, steady source of energy than glucose, which is derived from carbohydrates.


What is the keto diet? Rather than relying on counting calories, limiting portion sizes, resorting to extreme exercise or requiring lots of willpower (even in the face of drastically low energy levels), the ketogenic, low-carb diet takes an entirely different approach to weight loss and health improvements. It works because it changes the very œfuel source that the body uses to stay energized: namely, from burning glucose (or sugar) to dietary fat, courtesy of keto recipes and the ketogenic diet food list items, including high-fat, low-carb diet foods.
Bonnie J. Brehm, Randy J. Seeley, Stephen R. Daniels, and David A. D'Alessio, œA Randomized Trial Comparing a Very Low Carbohydrate Diet and a Calorie-Restricted Low Fat Diet on Body Weight and Cardiovascular Risk Factors in Healthy Women, The Journal of Clinical Endocrinology & Metabolism: Vol 88, No 4; January 14, 2009. http://press.endocrine.org/doi/full/10.1210/jc.2002-021480.

According to the USDA, a 100-gram serving of red tomatoes has 3.89 grams of carbohydrates.43 You may add this fruit to your ketogenic diet safely and gain its beneficial nutrients, particularly lycopene. Researchers from Ohio State University suggest that this antioxidant may help protect your skin from sun damage, which may result in a lowered risk of skin cancer tumors.44
The second way is called autophagy, and it goes hand in hand with letting your body rest from digestion. Autophagy is the process that cells use to remove waste, including malfunctioning parts of cells, or even whole cells that are not functioning correctly and can't be healed. If you have read much about cancer, this may sound like it's connected, and it is. Regularly allowing cells to be in a state of autophagy makes them more efficient and keeps them from growing into a malignant state. It also helps them to live longer, which translates to a longer, healthier life for you.
It's important to remember that the goal of any dietary change is to promote a healthy lifestyle, so make sure to select a meal plan you can envision yourself following long term. If you know you will not be able to comply with such stringent carbohydrate restrictions for years to come, the ketogenic diet is most likely not the right choice for you.

¢ Cancer: Early experimental research suggests that the keto diet may have anti-tumor effects, likely because it reduces overall calorie intake (and circulating glucose) for tumor growth. In one 2014 review of animal research, a ketogenic diet was found to be successful at reducing tumor growth, colon cancer, gastric cancer and brain cancer. More research on humans with larger sample sizes is needed, but it's definitely food for thought.
I've always heard that the brain functions well on ketones. Gluconeogenisis typically reduces ketosis, though as well? This is the first time I've heard anyone say the brain can't use anything but glucose. I know there's *preferred* sources of fuel over others, but I was also fairly certain other sources were fine.. or humans might be in a bit of trouble.

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