Yancy WS Jr, Westman EC, McDuffie JR, Grambow SC, Jeffreys AS, Bolton J, Chalecki A, Oddone EZ, œA randomized trial of a low-carbohydrate diet vs orlistat plus a lowfat diet for weight loss, Arch Intern Med. 2010 Jan 25;170(2):136-45. http://www.ncbi.nlm.nih.gov/pubmed/20101008?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=2.
Frederick F. Samaha, M.D., Nayyar Iqbal, M.D., Prakash Seshadri, M.D., Kathryn L. Chicano, C.R.N.P., Denise A. Daily, R.D., Joyce McGrory, C.R.N.P., Terrence Williams, B.S., Monica Williams, B.S., Edward J. Gracely, Ph.D., and Linda Stern, M.D., œA Low-Carbohydrate as Compared with a Low-Fat Diet in Severe Obesity, N Engl J Med 2003; 348:2074-2081. http://www.nejm.org/doi/full/10.1056/NEJMoa022637.

Certain studies suggest that ketogenic diets may œstarve cancer cells. A highly processed, pro-inflammatory, low-nutrient diet can feed cancer cells causing them to proliferate. What's the connection between a high-sugar diet and cancer? The regular cells found in our bodies are able to use fat for energy, but it's believed that cancer cells cannot metabolically shift to use fat rather than glucose. (11)


Con: Results can vary depending on how much fluid you drink. By drinking more water, you dilute the concentration of ketones in the urine and thus a lower level of ketones will be detected on the strips. The strips don't show a precise ketone level. Finally, and most importantly, as you become increasingly keto-adapted and your body reabsorbs ketones from the urine, urine strips may become unreliable, even if you're in ketosis.
Mistakes, refinements, pivots, corrections, whatever your want to call them¦ These changes are the vehicle that takes us from stage to stage of the Ketogenic Hierarchy of Needs. The good news is they are also the vehicle to break through plateaus and reach new performance levels. Changing habits is tough, no doubt about it, but have fun and go for it!
I've always heard that the brain functions well on ketones. Gluconeogenisis typically reduces ketosis, though as well? This is the first time I've heard anyone say the brain can't use anything but glucose. I know there's *preferred* sources of fuel over others, but I was also fairly certain other sources were fine.. or humans might be in a bit of trouble.

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