A related clinical diet for drug-resistant epilepsy is called the medium-chain triglyceride ketogenic diet, in which MCT oil is extensively used because it's more ketogenic than long-chain triglycerides. (13a) Another dietary therapy for epilepsy called Low Glycemic Index Treatment (LGIT) was developed in 2002 as an alternative to the ketogenic diet. LGIT monitors the total amount of carbohydrates consumed daily, and focuses on carbohydrates that have a low glycemic index.) (13b)
œYour liver produces ketones all the time, but the rate depends on carbohydrate and protein intake, says Jeff Volek, Ph.D., R.D., a professor of human sciences at Ohio State University. When the majority of your diet is made up of of carbs and protein, ketogenesis slows. Replacing carbs and protein with fat will put your body into ketosis, thus ramping up ketone production. This takes about three days to induce.
Alcohol also tends to interrupt ketosis, since your liver will burn it preferentially before anything else. Your body treats alcohol like a toxin and like a fuel source, so your body will use it before it uses foods or the calories stored in your fat cells. While it won't necessarily œknock you out of ketosis, it does pause it until the alcohol is cleared from your system.
Researchers believe that the ketogenic diet can also help patients with schizophrenia to normalize the pathophysiological processes that are causing symptoms like delusions, hallucinations, lack of restraint and unpredictable behavior. One study found that the ketogenic diet lead to elevated concentrations of kynurenic acid (KYNA) in the hippocampus and striatum, which promotes neuroactive activity. Some studies even point to the elimination of gluten under the ketogenic diet as a possible reason for improved symptoms, as researchers observed that patients with schizophrenia tended to eat more carbohydrates immediately before a psychotic episode. (15)
The best place to get started if you're interested in the ketogenic diet is to first take a look at the fats you can incorporate, such as avocado, olive oil, or cacao butter. You could also take a look at more of an animal-based fat like grass-fed tallow or pasteurized lard or, if you are not too sensitive to butter, grass-fed butter is a really good option.
#3: Next, calculate your protein requirements. If you are active, Target 0.8-1.2 g of protein per pound of weight. This is a simplified version of a complex calculation you can do, which is dependent on your lean body mass, how active you are, etc. If you have a lot of weight to lose, you'll wan to adjust this number down to more like 0.5-.6g per pound (consult the above calculator) You can multiply this by 4 to see how many calories total that would be.
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